Kim Dupree Jones

Kim Dupree Jones

Professor, tenured, Associate Dean of Academic Advancement | PhD, FNP, FAAN

About

Kim Dupree Jones, PhD, RN, FNP, FAAN, Professor, is a nationally renowned nurse scientist and educator, and the Associate Dean of Academic Advancement. Dr. Jones is a distinguished administrator and researcher with more than three decades of experience nursing education and research. She most recently served as Dean of the School of Nursing at Linfield University in Portland, Oregon. Prior to her appointment at Linfield University, she was a full professor in the School of Nursing at Oregon Health and Sciences University. Her BSN is from University of Tennessee; Her MN (FNP) is from Emory University; Her PhD and post-doctoral training are from Oregon Health & Science University.

Dr. Jones is recognized as a leading expert in fibromyalgia, where her work is cited in national and international treatment guidelines and texts including Up To Date, Cecil’s Textbook of Medicine, Physical Rehabilitation & Medicine, Kelly’s Textbook of Rheumatology and Neurology in Clinical Practice. She is aco-author on The Revised Fibromyalgia Impact Questionnaire (FIQR), which is used extensively by major pharmaceutical companies including Pfizer, Lily, Cypress, Ortho, and Jazz pharmaceuticals as the first of the fibromyalgia-indicated drugs were tested and brough to the FDA. She also holds a patent for a genomics-based peripheral blood marker for fibromyalgia. Her most recent work has two foci: the role of cannabinoids in opioid taper, and photosensitivity as a novel mechanism engaging pain-modulating systems.

Dr. Jones is a prolific author with more than 130 publications and has completed more than 60 scientific studies on fibromyalgia to date with funding from the National Institutes of Health, the U.S. Department of Defense, multiple foundations and industry.  She is recognized as a leading nurse researcher in pain management and is a fellow in the American Academy of Nursing and the Sigma Theta Tau International Nurse Researcher Hall of Fame.

During her four years as a Dean School of Nursing, Linfield University, she led major changes including moving all second-degree students to a novel 10-week academic calendar and launching a Masters Entry to Professional Nursing program, the first in Oregon. She also oversaw a move from their small historic campus to a 20 acre, 11building campus, with 700% increase in simulation space. She worked with faculty and the Oregon State Board of Nursing to optimize simulation, moving from 22% to 49% (maximum allowable). Working closely with the President and Provost, she successfully led faculty governance changes that included an inaugural Senate model of governance that decentralized Promotion & Tenure, Evaluation, and Curriculum. Follow Dr Jones on Twitter @kjnursingdean and Instagram @deanofnursing.

Areas of Expertise

Acute And Chronic Care
Biological Behavioral Omics
Methods
Sleep
Symptom Science

Publications

Balba, N., McBride, A.l., Jones, K.D., Callahan, M., Butler, M.,Lim, M., Heinricher, M. & Mist, S.D (in press) Photosensitivity Predicts High-Impact Chronic Pain after Traumatic Brain Injury. Journal of Neurotrauma

St John, A.W., Aebischer, J, Friend, R., & Jones, K.D. (inpress) Fibromyalgia: A clinical update. Aebischer, J, Dieckmann, N & Jones,K.D. Chronic pain clinical adaptation and prescriptive practices in the cannabis era. Pain Management Nursing. doi: 10.1016/j.pmn.2021.11.009

Bennett, R.M., Jones, K.D. StJohn, A.W., Aebischer, J., & Friend, R. (2021) Which symptoms best distinguish fibromyalgia patients from those with other chronic pain disorders? Journal of Evaluation in Clinical Practice. Sept 27 ePub ahead of print; PMID3450965

Rice,J. Hildebrand, A., Waslo, C., Cameron, M. and Jones, K.D. (2021) Cannabis for medical purposes: a cross-sectional analysis of health care professionals’ knowledge. Journal of the American Association of Nurse Practitioners. March19, ePub ahead of print. PMID: 33767121

Friend,R., Bennett, R.M., Aebischer, J.H., St John, A.R., Jones, K.D. (2021)Validating the revised Symptom Impact Questionnaire (SIQR) questionnaire with a proposed fibromyalgiaphenotype using experimentally induced pain and patient self-reports. Clinical and Experimental Rheumatology. May. PMID: 34001310 

Pfaltzgraph, A., Giannetti, V.,Lobo, C. & Jones, K.D. (2020) Use of Complementary and Alternative Medicinein Fibromyalgia: Results of an Online Survey. Pain Management Nursing. Sept3: S1524-9042(20) PMID: 32893131

Clauw, D.J., Essex, M.N., Pitman, V., & Jones,K.D. (2019) Reframing chronic pain as a disease, not a symptom: rationale and implications for pain management. Postgraduate Medicine. 131:3, 185-198, PMID:30700198

McCalmont, J.,Friend, R., Bennett, R.M. & Jones, K.D. (2018) Provider knowledge and attitudes regarding opioid prescribing in chronic non-cancer pain. Journal of Opioid Medicine. 14(2):103-116. PMID:29733096

Huang, E.R., Jones, K.D., Bennett, R.M.,Hall, G. & Lyons, K.S. (2018 ) The Role of Spousal Relationships in Fibromyalgia Patients’ Quality of Life. Psychology, Health & Medicine. Sep;23(8):987-995 MID:29471682

Mist, S.D., & Jones,K.D (2018) Randomized trial of acupuncturefor women with fibromyalgia” Group acupuncture with traditional Chinese medicinediagnosis-based point selection. PainMedicine. Sep 1;19(9):1862-1871PMID:29447382 Editorial byZheng, Z (2018) What have we learnt from acupuncture research of fibromyalgia? Longhua Chin Med 1:14 doi: 10.21037/lcm.2018.10.01

Jones, K.D., Baggs, J & Jones, M. (2017)Selecting US Research-intensive Doctoral Programs in Nursing: Pragmatic Questions for Potential Applicants. Journal of Professional Nursing. 34(4):296-299.PMID: 30055683

Jones, K.D., Aebischer, J.H., St John, A.R., Friend,R., Bennett, R.M. (2018) Screening pain patients for a diagnosis of fibromyalgia in primary care. J of Evaluation in Clinical Practice, 24(1): 173-179. PMID:29063661

Teaching

Dr. Jones is an award-winning educator. As faculty she has taught and developed curriculum in pre-licensure, Masters, FNP, PhD, interprofessional programs and co-developed the first DNP program in Oregon. She has mentored over 30 pre-doctoral students, post-doctoral fellows and K-scientists from across the globe including publishing with students and trainees. She has served as Invited Visiting Faculty, The Parker Institute, Copenhagen, Denmark(2009) and Mahidol University, Bangkok, Thailand (2016). She has developed mentorship and teaching programs for new faculty and has received awards for teaching including Nurse of the Year, Teaching Award, All Oregon Higher Education (2017) and Outstanding Graduate Faculty Award  for Teaching Innovation, OHSU (2009). Her greatest joy is watching her former students and current faculty succeed, many of whom are now researchers, deans,program directors, policy leaders and clinical experts.

Research

Our research team  has produced data that increased the understanding of neuroendocrine  dysfunction and exercise intolerance in people with fibromyalgia.  Specifically, we developed and tested exercise modifications given our  finding that 90% of people with fibromyalgia fail to mount a normal growth  hormone (GH) response to exercise at VO2 peak, have low baseline insulin-like  growth factor (IGF-1) adjusted for age. We also demonstrated GH normalization  in response to a variety of drugs that alter the tonic balance between growth  hormone releasing hormone and somatostatin. These findings were first  reported by our team and since replicated by others. Inadequate growth  hormone release may result in perturbed muscle repair after exercise. The  resulting delayed onset muscle soreness may be interpreted as deep aching  pain due to enhanced central processing (Jones, PI, NIAMS R01). This line of  inquiry has been furthered by our discovery that women with fibromyalgia fail  to produce expected anti-inflammatory/cytokine response to exercise (Jones  & Wood Co-PIs, NINR R21). These finding have implications for why  patients may experience severe fatigue after overexertion. We have tested  multiple pharmacologic interventions prior to exercise that correct  neuroendocrine deficits acutely (e.g., pyridostigmine bromide), but failed to  move biomarkers farther downstream (e.g., IGF-1). Relatedly, we completed an  R-21 funded genome-wide expression profile of the peripheral blood of women  with fibromyalgia. In addition to the expected findings relevant to pathways  for pain processing (glutamine/glutamate signaling and axonal development),  there was also novel upregulation of several inflammatory pathways and down regulation of pathways related to hypersensitivity.

Low-intensity standard exercise (aerobics/strength/flexibility) has been  demonstrated by us and others to improve physical fitness/function, pain and  stiffness, but does little to improve unrefreshing sleep. Moreover, symptom  improvements waned after the intervention, as participants did not continue  their practice. This gap led us to develop and test complementary mind/body  movement interventions in fibromyalgia. In separate studies, we demonstrated  that Tai chi and yoga do indeed result in significant symptom relief,  including sleep, while also providing robust improvement in strength,  flexibility and balance. We hypothesize that the mindful portions of these  modalities can be practiced ‘off the mat’ and move people toward positive  cognitive reframing. But ‘off the shelf’ mindfulness-based stress reduction  protocols need to be edited in response to our findings that people with  fibromyalgia may have non-mindful observations to sound, sight, smell, and  touch, perhaps related to enhanced central processing. All our trials are  anchored by our published multi-step recruitment process that yields <9%  attrition in complex drug/exercise trials (Jones, K.D. et al., 2010, Applied  Nursing Research.23 (4):227-32).

Our neurosensory analysis work, first in fibromyalgia, demonstrated that the  average 40 year old with fibromyalgia has balance scores predicted for an 80  year old. Further, the relative deficits in somatosensory, visual and  vestibular systems, mirror accelerated aging. We have also documented other  fall-related risk factors, poor physical function status and extreme  deconditioning in these patients. We leverage these data to design and test  exercise interventions across the age-span that are sensitive to deficits in  aerobic, strength, flexibility and balance.

Our team developed and tested The Revised Fibromyalgia Impact Questionnaire  (FIQ-R). We updated the original questionnaire (also developed by our team)  as more recent data have confirmed the importance of problems not previously  assessed such as poor balance, tenderness to touch, dyscognition, and  sensitivity to bright light/loud noise. The FIQ-R has adapted to other  cultures, has been translated to 9 languages and modified for use in  children. It has been used in 38 clinical trials registered on  clinical trials.gov and has significant adoption internationally. We developed  a fibromyalgia-neutral version of the FIQ-R (SIQ-R, Symptom Impact Questionnaire)  for use in other pain populations. We are currently using the SIQ-R in our  Department of Defense funded work with veterans who have pain associated with  mild traumatic brain injury. The SIQ-R questionnaire is now being used in  primary care, particularly to screen for fibromyalgia among those with other  chronic pain states reflecting the clinical and translational impact of this  research.

Awards

2021 International Nurse Researcher Hall of Fame

2021 Sigma International Nursing Honor Society

2019 Women Who Move the City Award

2018 Fellow of the Western Academy of Nurses (FWAN)

2017 Janet G Travell Award- For Research Excellence in Myofascial Pain

2010 Fellow of the American Academy of Nursing (FAAN)